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Rich harvest for Slovenian science and technology
Laboratory for refrigeration and district energy at Ljubljana's Faculty of Mechanical Engineering. Photo: Faculty of Mechanical Engineering

The key developments published last fall by Slovenian researchers include a new cooling technology, important advancements in gene therapies, and the discovery of microplastics in the exosphere.

A team of researchers from the National Institute of Chemistry (NIC) in Ljubljana has developed a new technology for chemical regulation of biological processes based on human proteins. The new technology called INSPIRE (inducible split protein regulators) could represent a pivotal step in cell and gene therapies. The technology enables the regulation of therapeutic cells via small molecules, either the body's own or those introduced into the body. As these molecules are based on human protein they are less likely to trigger an unwanted immune response.

The team at the Faculty of Mechanical Engineering in Ljubljana has made a significant advancement in the development of a new cooling (and heating) technology. The “world’s first” elastocaloric regenerator has exceptional cooling and heating characteristics and is much more effective (and thus environmentally friendly) than the existing vapour-compression technology. The authors are convinced that their discoveries are also applicable in medicine, construction, and mechanical engineering.

Researchers of the Clinical Institute of Medical Genetics in Ljubljana published data on two genes related to two grave human health conditions: a disease linked to developmental nerve system abnormalities in children and a severe heart muscle disease. The team used state-of-the art gene sequencing methods to prove that both diseases are caused by a change in the gene.

Another world’s first: a group of Slovenian researchers were the first to find traces of microplastic in hailstones. The results of their analysis suggest that microplastic may contribute to the formation of large ice balls or lumps. The research also proves that polyester fibrous particles can travel several thousand kilometres above the earth’s surface.

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